Explore the new Crnic Institute Human Trisome Project Virtual Biorepository (VBR)
The VBR enables users to request biospecimens from the Human Trisome Project biorepository.
Research opportunities for people with Down syndrome
Our research initiatives include clinical trials for immune skin conditions, Down Syndrome Regression Disorder (DSRD) and more.
Helping lead the NIH data coordinating center for Down syndrome research
Our scientists, data analysts, and administrators have teamed up with Children's Hospital of Philadelphia and Sage Bionetworks for this new initiative
We use state-of-the-art, transformational research platforms to decipher the unique biology and disease spectrum caused by trisomy of chromosome 21.
Our ultimate goal is to enable precision medicine approaches to improve health outcomes in Down syndrome, including the development of new diagnostic and therapeutic tools.​​​
We are the largest geographical cluster of Down syndrome researchers in the world​
Comprised of over 50 Principal Investigators and countless more contributing scientists from across the University of Â鶹´«Ã½¸ßÇå campuses, our researchers bring expertise from a variety of fields.
Together, we are working to decipher the complex mechanisms and multi-faceted health impacts of trisomy 21.
NIH announces relaunch of DS-Connect®: The Down Syndrome Registry
Last year, DS-Connect temporarily paused operations as NIH made plans for a refresh, selecting the University of Â鶹´«Ã½¸ßÇå Denver as the registry’s new service provider.
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Dr. Joaquin Espinosa featured in the Washington Post
Dr. Joaquin Espinosa, executive director of the Crnic Institute, discusses the devastating condition known as Down syndrome regression disorder (DSRD) and the exciting new clinical trial investigating potential treatments.
A Global Approach to Down Syndrome Research
The Human Trisome Project - Latin America Network is a unique collaboration between the Linda Crnic Institute for Down Syndrome and multiple hospitals and universities across Latin America.
Breakthrough Study Reveals Molecular Subtypes of Down Syndrome
The research identifies distinct molecular and immune subtypes across individuals with Down syndrome, offering new insights for personalized medicine approaches.
